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Product details

NBR1 Monoclonal Antibody

Catalog number E-AB-22148-01

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Price for E-AB-22148-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-22148-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.NBR1 (NBR1, Autophagy Cargo Receptor) is a Protein Coding gene. Diseases associated with NBR1 include Inclusion Body Myositis and Synucleinopathy. Among its related pathways are Mitophagy - animal. GO annotations related to this gene include ubiquitin binding and mitogen-activated protein kinase binding.
Abbreviation
NBR1
UniProt
Q14596
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Protein of NBR1
Target
1A1 3B;1A13B; B box protein; Cell migration-inducing gene 19 protein; KIAA0049; M17S2; Membrane component chromosome 17 surface marker 2; Membrane component; chromosome 17; surface marker 2 (ovarian carcinoma antigen CA125) ; MIG 19; MIG19; Migration inducing protein 19; NBR 1; Nbr1; NBR1; autophagy cargo receptor; NBR1; Neighbor of BRCA1 gene 1; Neighbor of BRCA1 gene 1 protein; Next to BRCA1 gene 1 protein; Ovarian carcinoma antigen CA125; Protein 1A1-3B
Clonality
Monoclonal
Clone
Clone:4C6
Conjugation
Unconjugated
Applications
IHC-p; IF
Field of Research
Cancer; Cell Biology
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
IHC 1:50-300; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for NBR1 Monoclonal Antibody?

The catalog number for NBR1 Monoclonal Antibody is E-AB-22148.

What sizes are available for NBR1 Monoclonal Antibody?

NBR1 Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does NBR1 Monoclonal Antibody come in?

NBR1 Monoclonal Antibody is available in 4 different pack sizes.

Is NBR1 Monoclonal Antibody in stock?

NBR1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NBR1 Monoclonal Antibody?

NBR1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for NBR1 Monoclonal Antibody?

Estimated delivery time for NBR1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NBR1 Monoclonal Antibody?

The safety data sheet for NBR1 Monoclonal Antibody is available here: https://789.bio/eb/yfHiPS.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

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