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Product details

P70 S6 kinase alpha Monoclonal Antibody

Catalog number E-AB-22198-01

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Price for E-AB-22198-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-22198-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
P70 S6 Kinase alpha is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases and contains 2 non-identical kinase catalytic domains. It phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein is activated by serine/threonine phosphorylation and protein kinase C and inactivated by type 2A phosphatase. Activation leads to an increase in protein synthesis and cell proliferation. Overexpression of this kinase is involved in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.
Abbreviation
P70 S6 kinase alpha
UniProt
P23443
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Protein of P70 S6 Kinase of RPS6KB1
Target
70 kDa ribosomal protein S6 kinase 1; KS6B1; p70 alpha; P70 beta 1; p70 ribosomal S6 kinase alpha; p70 ribosomal S6 kinase beta 1; p70 S6 kinase alpha; P70 S6 Kinase; p70 S6 kinase; alpha 1; p70 S6 kinase; alpha 2; p70 S6K; p70 S6K-alpha; p70 S6KA; p70 (S6K) alpha; p70 (S6K) -alpha; p70-alpha; p70-S6K 1; p70-S6K; P70S6K; P70S6K1; p70S6Kb; PS6K; Ribosomal protein S6 kinase 70kDa polypeptide 1; Ribosomal protein S6 kinase beta 1; Ribosomal protein S6 kinase beta-1; Ribosomal protein S6 kinase I; RPS6KB1; S6K; S6K-beta-1; S6K1; Serine/threonine kinase 14 alpha; Serine/threonine-protein kinase 14A; STK14A
Clonality
Monoclonal
Clone
Clone:1C7
Conjugation
Unconjugated
Applications
IHC-p
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Metabolism; Signal Transduction
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
IHC 1:100-200
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for P70 S6 kinase alpha Monoclonal Antibody?

The catalog number for P70 S6 kinase alpha Monoclonal Antibody is E-AB-22198.

What sizes are available for P70 S6 kinase alpha Monoclonal Antibody?

P70 S6 kinase alpha Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does P70 S6 kinase alpha Monoclonal Antibody come in?

P70 S6 kinase alpha Monoclonal Antibody is available in 4 different pack sizes.

Is P70 S6 kinase alpha Monoclonal Antibody in stock?

P70 S6 kinase alpha Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures P70 S6 kinase alpha Monoclonal Antibody?

P70 S6 kinase alpha Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for P70 S6 kinase alpha Monoclonal Antibody?

Estimated delivery time for P70 S6 kinase alpha Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for P70 S6 kinase alpha Monoclonal Antibody?

The safety data sheet for P70 S6 kinase alpha Monoclonal Antibody is available here: https://789.bio/eb/PKKmHG.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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