STAT1 Monoclonal Antibody

Catalog number E-AB-22205-01

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Price for E-AB-22205-01

Size / count 20 µL

Specifications

Catalog number: E-AB-22205-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Signal transducer and activator of transcription that mediates signaling by interferons (IFNs) . Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state.
Abbreviation: STAT1 Mouse (5H7)
UniProt: P42224
Host: Mouse
Reactivity: Human; Mouse; Rat
Immunogen: Synthetic Peptide of STAT1
Target: Signal transducer and activator of transcription 1 91kD; CANDF7; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF 3; ISGF-3; OTTHUMP00000163552; OTTHUMP00000165046; OTTHUMP00000165047; OTTHUMP00000205845; Signal transducer and activator of transcription 1 91kDa; Signal transducer and activator of transcription 1; Signal transducer and activator of transcription 1;91kD; Signal transducer and activator of transcription 1-alpha/beta; STAT 1; Stat1; STAT1; STAT91; Transcription factor ISGF 3 components p91 p84; Transcription factor ISGF-3 components p91/p84
Clonality: Monoclonal
Clone: Clone:5H7
Conjugation: Unconjugated
Applications: IHC-p
Field of Research: Cancer; Epigenetics and Nuclear Signaling; Signal Transduction
Purification: Protein A purification
Concentration: 1 mg/mL
Dilution: IHC 1:100-200
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for STAT1 Monoclonal Antibody?

The catalog number for STAT1 Monoclonal Antibody is E-AB-22205.

What sizes are available for STAT1 Monoclonal Antibody?

STAT1 Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does STAT1 Monoclonal Antibody come in?

STAT1 Monoclonal Antibody is available in 4 different pack sizes.

Is STAT1 Monoclonal Antibody in stock?

STAT1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures STAT1 Monoclonal Antibody?

STAT1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for STAT1 Monoclonal Antibody?

Estimated delivery time for STAT1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for STAT1 Monoclonal Antibody?

The safety data sheet for STAT1 Monoclonal Antibody is available here: https://789.bio/eb/GKavjP.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.