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Product details

SGK1 Monoclonal Antibody

Catalog number E-AB-22207-01

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Price for E-AB-22207-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-22207-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Protein kinase that plays an important role in cellular stress response. Activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion. Sustained high levels and activity may contribute to conditions such as hypertension and diabetic nephropathy. Mediates cell survival signals, phosphorylates and negatively regulates pro-apoptotic FOXO3A. Phosphorylates NEDD4L, which leads to its inactivation and to the subsequent activation of various channels and transporters such as ENaC, KCNA3/Kv1.3 or EAAT1. Isoform 2 exhibited a greater effect on cell plasma membrane expression of ENaC and Na (+) transport than isoform 1.
Abbreviation
SGK1 Mouse (4D12)
UniProt
O00141
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic Peptide of SGK1
Target
OTTHUMP00000017247; Serine/threonine protein kinase SGK; Serine/threonine protein kinase Sgk1; Serine/threonine-protein kinase Sgk1; Serum and glucocorticoid regulated kinase; Serum/glucocorticoid regulated kinase 1; Serum/glucocorticoid regulated kinase; Serum/glucocorticoid-regulated kinase 1; SGK 1; SGK; SGK1; Sgk1 variant i3; SGK1
Clonality
Monoclonal
Clone
Clone:4D12
Conjugation
Unconjugated
Applications
IHC-p
Field of Research
Cancer; Developmental Biology; Signal Transduction; Stem Cells
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
IHC 1:100-200
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for SGK1 Monoclonal Antibody?

The catalog number for SGK1 Monoclonal Antibody is E-AB-22207.

What sizes are available for SGK1 Monoclonal Antibody?

SGK1 Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does SGK1 Monoclonal Antibody come in?

SGK1 Monoclonal Antibody is available in 4 different pack sizes.

Is SGK1 Monoclonal Antibody in stock?

SGK1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SGK1 Monoclonal Antibody?

SGK1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for SGK1 Monoclonal Antibody?

Estimated delivery time for SGK1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SGK1 Monoclonal Antibody?

The safety data sheet for SGK1 Monoclonal Antibody is available here: https://789.bio/eb/jDefHC.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

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