CASP3 Monoclonal Antibody

Catalog number E-AB-22209-01

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Price for E-AB-22209-01

Size / count 20 µL

Specifications

Catalog number: E-AB-22209-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
Abbreviation: CASP3
UniProt: P42574
Host: Mouse
Reactivity: Human; Mouse; Rat
Immunogen: Synthetic Peptide of Caspase-3
Target: A830040C14Rik; Apopain; CASP-3; CASP3; CASP3; Casp3a; Caspase 3; Caspase 3; apoptosis-related cysteine peptidase; Caspase 3; apoptosis-related cysteine protease; Caspase 3; apoptosis-related cysteine protease a; Caspase-3 subunit p12; CC3; CPP-32; CPP32; CPP32B; Cysteine protease CPP32; EC 3.4.22.56; LICE; mldy; OTTHUMP00000165052; OTTHUMP00000165053; OTTHUMP00000165054; PARP cleavage protease; Procaspase3; Protein Yama; SCA 1; SCA-1; SREBP cleavage activity 1; Yama
Clonality: Monoclonal
Clone: Clone:4B8
Conjugation: Unconjugated
Applications: IHC-p
Field of Research: Cancer; Cell Biology; Metabolism; Neuroscience
Purification: Protein A purification
Concentration: 1 mg/mL
Dilution: IHC 1:100-200
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Citation 01: https://www.sciencedirect.com/science/article/pii/S0753332220302663
Isotype: IgG

Frequently Asked Questions

What is the catalog number for CASP3 Monoclonal Antibody?

The catalog number for CASP3 Monoclonal Antibody is E-AB-22209.

What sizes are available for CASP3 Monoclonal Antibody?

CASP3 Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does CASP3 Monoclonal Antibody come in?

CASP3 Monoclonal Antibody is available in 4 different pack sizes.

Is CASP3 Monoclonal Antibody in stock?

CASP3 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CASP3 Monoclonal Antibody?

CASP3 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CASP3 Monoclonal Antibody?

Estimated delivery time for CASP3 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CASP3 Monoclonal Antibody?

The safety data sheet for CASP3 Monoclonal Antibody is available here: https://789.bio/eb/GOCqL0.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.