Product details

AKT1 Monoclonal Antibody

Catalog number E-AB-22210-01

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Price for E-AB-22210-01

Size / count 20 µL

Specifications

Catalog number: E-AB-22210-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.
Abbreviation: AKT1
UniProt: P31749
Host: Mouse
Reactivity: Human
Immunogen: Synthetic Peptide of AKT1
Target: AKT 1; AKT; AKT1; AKT1; MGC99656; PKB; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha; RAC; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha
Clonality: Monoclonal
Clone: Clone:10D6
Conjugation: Unconjugated
Applications: WB
Field of Research: Cancer; Epigenetics and Nuclear Signaling; Metabolism; Signal Transduction
Purification: Protein A purification
Concentration: 1 mg/mL
Dilution: WB 1:1000-2000
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight: 60kDa
Citation 01: https://www.sciencedirect.com/science/article/pii/S0753332220310209
Isotype: IgG

Frequently Asked Questions

What is the catalog number for AKT1 Monoclonal Antibody?

The catalog number for AKT1 Monoclonal Antibody is E-AB-22210.

What sizes are available for AKT1 Monoclonal Antibody?

AKT1 Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does AKT1 Monoclonal Antibody come in?

AKT1 Monoclonal Antibody is available in 4 different pack sizes.

Is AKT1 Monoclonal Antibody in stock?

AKT1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AKT1 Monoclonal Antibody?

AKT1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for AKT1 Monoclonal Antibody?

Estimated delivery time for AKT1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for AKT1 Monoclonal Antibody?

The safety data sheet for AKT1 Monoclonal Antibody is available here: https://789.bio/eb/PKGSu1.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.