TGFB1 Monoclonal Antibody

Catalog number E-AB-22214-01

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Price for E-AB-22214-01

Size / count 20 µL

Specifications

Catalog number: E-AB-22214-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells.
Abbreviation: TGFβ1 Mouse (5D2)
UniProt: P01137
Host: Mouse
Reactivity: Mouse; Rat
Immunogen: Synthetic Peptide of TGFβ1
Target: Cartilage-inducing factor; CED; Differentiation inhibiting factor; DPD1; LAP; Latency-associated peptide; Prepro transforming growth factor beta 1; TGF beta 1; TGF beta; TGF beta 1 protein; TGF-beta 1 protein; TGF-beta-1; TGF-beta-5; TGF-beta1; TGFB; Tgfb-1; tgfb1; TGFB1; TGFbeta; TGFbeta1; Transforming Growth Factor b1; Transforming Growth Factor beta 1; Transforming growth factor beta 1a; transforming growth factor beta-1; transforming growth factor; beta 1; Transforming Growth Factor-1
Clonality: Monoclonal
Clone: Clone:5D2
Conjugation: Unconjugated
Applications: IHC-p
Field of Research: Cancer; Cardiovascular; Metabolism; Signal Transduction; Stem Cells
Purification: Protein A purification
Concentration: 1 mg/mL
Dilution: IHC 1:100-200
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for TGFB1 Monoclonal Antibody?

The catalog number for TGFB1 Monoclonal Antibody is E-AB-22214.

What sizes are available for TGFB1 Monoclonal Antibody?

TGFB1 Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does TGFB1 Monoclonal Antibody come in?

TGFB1 Monoclonal Antibody is available in 4 different pack sizes.

Is TGFB1 Monoclonal Antibody in stock?

TGFB1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TGFB1 Monoclonal Antibody?

TGFB1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for TGFB1 Monoclonal Antibody?

Estimated delivery time for TGFB1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TGFB1 Monoclonal Antibody?

The safety data sheet for TGFB1 Monoclonal Antibody is available here: https://789.bio/eb/qPubnT.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.