GSK3 beta Monoclonal Antibody — image 1 of 2

Product details

GSK3 beta Monoclonal Antibody

Catalog number E-AB-22221-01

Choose a variant (4 options)

Selecting a variant updates its price, size and availability.

Price for E-AB-22221-01

Size / count 20 µL

Specifications

Catalog number: E-AB-22221-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Phosphorylates MACF1 and this phosphorylation inhibits the binding of MACF1 to microtubules which is critical for its role in bulge stem cell migration and skin wound repair.
Abbreviation: GSK3 beta
UniProt: P49841
Host: Mouse
Reactivity: Human; Mouse; Rat
Immunogen: Synthetic Peptide of GSK3β
Target: Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3B; GSK3B; GSK3beta isoform; Serine/threonine-protein kinase GSK3B
Clonality: Monoclonal
Clone: Clone:4D2
Conjugation: Unconjugated
Applications: WB; IHC-p
Field of Research: Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Purification: Protein A purification
Concentration: 1 mg/mL
Dilution: WB 1:1000-2000; IHC 1:100-200
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight: 46kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for GSK3 beta Monoclonal Antibody?

The catalog number for GSK3 beta Monoclonal Antibody is E-AB-22221.

What sizes are available for GSK3 beta Monoclonal Antibody?

GSK3 beta Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does GSK3 beta Monoclonal Antibody come in?

GSK3 beta Monoclonal Antibody is available in 4 different pack sizes.

Is GSK3 beta Monoclonal Antibody in stock?

GSK3 beta Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GSK3 beta Monoclonal Antibody?

GSK3 beta Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for GSK3 beta Monoclonal Antibody?

Estimated delivery time for GSK3 beta Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GSK3 beta Monoclonal Antibody?

The safety data sheet for GSK3 beta Monoclonal Antibody is available here: https://789.bio/eb/D4W9uT.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.