Cleaved-CASP3 p17 (D175) Polyclonal Antibody — image 1 of 2

Product details

Cleaved-CASP3 p17 (D175) Polyclonal Antibody

Catalog number E-AB-30004-01

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Price for E-AB-30004-01

Size / count 20 µL

Specifications

Catalog number: E-AB-30004-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
Abbreviation: Cleaved-Caspase-3 p17 (D175)
UniProt: P42574
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Synthesized peptide derived from the Internal region of human Caspase-3 p17
Target: A830040C14Rik; Apopain; CASP-3; CASP3; CASP3; Casp3a; Caspase 3; Caspase 3; apoptosis-related cysteine peptidase; Caspase 3; apoptosis-related cysteine protease; Caspase 3; apoptosis-related cysteine protease a; Caspase-3 subunit p12; CC3; CPP-32; CPP32; CPP32B; Cysteine protease CPP32; EC 3.4.22.56; LICE; mldy; OTTHUMP00000165052; OTTHUMP00000165053; OTTHUMP00000165054; PARP cleavage protease; Procaspase3; Protein Yama; SCA 1; SCA-1; SREBP cleavage activity 1; Yama
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC-p; IF
Field of Research: Cancer; Cell Biology; Metabolism; Neuroscience
Purification: Affinity purification
Concentration: 1 mg/mL
Dilution: WB 1:500-2000; IHC 1:50-300; IF 1:50-300
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 32kDa
Observed Molecular Weight: 20kDa
Citation 01: https://www.frontiersin.org/articles/10.3389/fonc.2021.735183/full
Citation 02: https://www.mdpi.com/1422-0067/23/18/10411
Citation 03: https://www.mdpi.com/1065770
Citation 04: https://www.sciencedirect.com/science/article/pii/S0753332220302456
Citation 05: https://link.springer.com/article/10.1007/s11696-019-00894-8
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Cleaved-CASP3 p17 (D175) Polyclonal Antibody?

The catalog number for Cleaved-CASP3 p17 (D175) Polyclonal Antibody is E-AB-30004.

What sizes are available for Cleaved-CASP3 p17 (D175) Polyclonal Antibody?

Cleaved-CASP3 p17 (D175) Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does Cleaved-CASP3 p17 (D175) Polyclonal Antibody come in?

Cleaved-CASP3 p17 (D175) Polyclonal Antibody is available in 4 different pack sizes.

Is Cleaved-CASP3 p17 (D175) Polyclonal Antibody in stock?

Cleaved-CASP3 p17 (D175) Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cleaved-CASP3 p17 (D175) Polyclonal Antibody?

Cleaved-CASP3 p17 (D175) Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Cleaved-CASP3 p17 (D175) Polyclonal Antibody?

Estimated delivery time for Cleaved-CASP3 p17 (D175) Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cleaved-CASP3 p17 (D175) Polyclonal Antibody?

The safety data sheet for Cleaved-CASP3 p17 (D175) Polyclonal Antibody is available here: https://789.bio/eb/LWDuvP.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.