Cleaved-NOTCH1 (V1754) Polyclonal Antibody

Catalog number E-AB-30054-01

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Price for E-AB-30054-01

Size / count 20 µL

Specifications

Catalog number: E-AB-30054-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.
Abbreviation: Cleaved-NOTCH1 (V1754)
UniProt: P46531
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Synthesized peptide derived from the Internal region of human Notch 1
Target: HN1; Neurogenic locus Notch homolog protein 1; NICD; NOTC1; Notch 1; Notch 1 intracellular domain; Notch homolog 1 translocation associated (Drosophila) ; notch1; TAN1; Translocation-associated notch protein TAN-1
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC-p; IF
Field of Research: Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Developmental Biology; Neuroscience; Stem Cells
Purification: Affinity purification
Concentration: 1mg/mL
Dilution: WB 1:500-2000; IHC 1:50-300; IF 1:50-300
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 273kDa
Observed Molecular Weight: 110kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Cleaved-NOTCH1 (V1754) Polyclonal Antibody?

The catalog number for Cleaved-NOTCH1 (V1754) Polyclonal Antibody is E-AB-30054.

What sizes are available for Cleaved-NOTCH1 (V1754) Polyclonal Antibody?

Cleaved-NOTCH1 (V1754) Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does Cleaved-NOTCH1 (V1754) Polyclonal Antibody come in?

Cleaved-NOTCH1 (V1754) Polyclonal Antibody is available in 4 different pack sizes.

Is Cleaved-NOTCH1 (V1754) Polyclonal Antibody in stock?

Cleaved-NOTCH1 (V1754) Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cleaved-NOTCH1 (V1754) Polyclonal Antibody?

Cleaved-NOTCH1 (V1754) Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Cleaved-NOTCH1 (V1754) Polyclonal Antibody?

Estimated delivery time for Cleaved-NOTCH1 (V1754) Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cleaved-NOTCH1 (V1754) Polyclonal Antibody?

The safety data sheet for Cleaved-NOTCH1 (V1754) Polyclonal Antibody is available here: https://789.bio/eb/fbbvvH.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.