RUNX2 Polyclonal Antibody

Catalog number E-AB-30103-01

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Price for E-AB-30103-01

Size / count 20 µL

Specifications

Catalog number: E-AB-30103-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1 (I) collagen, LCK, IL-3 and GM-CSF promoters (By similarity) . Inhibits MYST4-dependent transcriptional activation.
Abbreviation: RUNX2
UniProt: Q13950
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Synthesized peptide derived from the Internal region of human RUNX2.
Target: Acute myeloid leukemia 3 protein; Alpha subunit 1; AML3; CBF alpha 1; CBF-alpha-1; CBFA1; CCD; CCD1; Cleidocranial dysplasia 1; Core binding factor; Core binding factor runt domain alpha subunit 1; Core binding factor subunit alpha 1; Core-binding factor subunit alpha-1; MGC120022; MGC120023; Oncogene AML 3; Oncogene AML-3; OSF 2; OSF-2; OSF2; Osteoblast specific transcription factor 2; Osteoblast-specific transcription factor 2; OTTHUMP00000016533; PEA2 alpha A; PEA2-alpha A; PEA2aA; PEBP2 alpha A; PEBP2-alpha A; PEBP2A1; PEBP2A2; PEBP2aA; PEBP2aA1; Polyomavirus enhancer binding protein 2 alpha A subunit; Polyomavirus enhancer-binding protein 2 alpha A subunit; Runt domain; Runt related transcription factor 2; Runt-related transcription factor 2; RUNX2; RUNX2; SL3 3 enhancer factor 1 alpha A subunit; SL3-3 enhancer factor 1 alpha A subunit; SL3/AKV core binding factor alpha A subunit; SL3/AKV core-binding factor alpha A subunit
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IF
Field of Research: Cancer; Epigenetics and Nuclear Signaling; Developmental Biology; Stem Cells
Purification: Affinity purification
Concentration: 1mg/mL
Dilution: WB 1:500-1:2000; IF 1:50-1:200
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 57kDa
Observed Molecular Weight: 56kDa
Citation 01: https://www.sciencedirect.com/science/article/pii/S0006295222003781
Citation 02: https://onlinelibrary.wiley.com/doi/abs/10.1111/jre.12973
Citation 03: https://onlinelibrary.wiley.com/doi/abs/10.1111/odi.14218
Isotype: IgG

Frequently Asked Questions

What is the catalog number for RUNX2 Polyclonal Antibody?

The catalog number for RUNX2 Polyclonal Antibody is E-AB-30103.

What sizes are available for RUNX2 Polyclonal Antibody?

RUNX2 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does RUNX2 Polyclonal Antibody come in?

RUNX2 Polyclonal Antibody is available in 4 different pack sizes.

Is RUNX2 Polyclonal Antibody in stock?

RUNX2 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RUNX2 Polyclonal Antibody?

RUNX2 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for RUNX2 Polyclonal Antibody?

Estimated delivery time for RUNX2 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for RUNX2 Polyclonal Antibody?

The safety data sheet for RUNX2 Polyclonal Antibody is available here: https://789.bio/eb/5unTuL.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.