ERK 1/2 Polyclonal Antibody

Catalog number E-AB-31374-01

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Price for E-AB-31374-01

Size / count 20 µL

Specifications

Catalog number: E-AB-31374-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2) . Phosphorylates SPZ1 (By similarity) . Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
Abbreviation: ERK 1/2
UniProt: P27361, P28482
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Synthesized peptide derived from the C-terminal region of human ERK 1/2
Target: MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC-p; IF
Field of Research: Cancer; Signal Transduction; Neuroscience
Purification: Affinity purification
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:50-1:200
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 43kDa
Observed Molecular Weight: 42,44kDa
Citation 01: https://www.mdpi.com/article/10.3390/cells12010115
Citation 02: https://www.mdpi.com/1492614
Citation 03: https://www.frontiersin.org/articles/10.3389/fphys.2020.00403/full?report=reader
Isotype: IgG

Frequently Asked Questions

What is the catalog number for ERK 1/2 Polyclonal Antibody?

The catalog number for ERK 1/2 Polyclonal Antibody is E-AB-31374.

What sizes are available for ERK 1/2 Polyclonal Antibody?

ERK 1/2 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does ERK 1/2 Polyclonal Antibody come in?

ERK 1/2 Polyclonal Antibody is available in 4 different pack sizes.

Is ERK 1/2 Polyclonal Antibody in stock?

ERK 1/2 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ERK 1/2 Polyclonal Antibody?

ERK 1/2 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for ERK 1/2 Polyclonal Antibody?

Estimated delivery time for ERK 1/2 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ERK 1/2 Polyclonal Antibody?

The safety data sheet for ERK 1/2 Polyclonal Antibody is available here: https://789.bio/eb/z10q98.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.