MMP2 Polyclonal Antibody

Catalog number E-AB-32054-01

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Price for E-AB-32054-01

Size / count 20 µL

Specifications

Catalog number: E-AB-32054-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro.PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels.
Abbreviation: MMP-2
UniProt: P08253
Host: Rabbit
Reactivity: Human; Mouse; Rat; Monkey
Immunogen: Synthesized peptide derived from the C-terminal region of human MMP-2
Target: 72 kDa gelatinase;72kD type IV collagenase; CLG 4; CLG 4A; CLG4; CLG4A; Collagenase Type 4 alpha; Collagenase type IV A; Gelatinase A; Gelatinase alpha; Gelatinase neutrophil; Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase; Matrix metalloproteinase 2 (gelatinase A;72kDa gelatinase;72kDa type IV collagenase) ; Matrix Metalloproteinase 2; Matrix metalloproteinase II; Matrix metalloproteinase-2; MMP 2; MMP II; MMP-2; MMP2; MMP2; MONA; Neutrophil gelatinase; PEX; TBE 1; TBE-1
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC-p; IF
Field of Research: Cancer; Cell Biology; Cardiovascular; Metabolism
Purification: Affinity purification
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 74kDa
Observed Molecular Weight: 74kDa
Citation 01: https://link.springer.com/article/10.1007/s11655-018-2985-3
Isotype: IgG

Frequently Asked Questions

What is the catalog number for MMP2 Polyclonal Antibody?

The catalog number for MMP2 Polyclonal Antibody is E-AB-32054.

What sizes are available for MMP2 Polyclonal Antibody?

MMP2 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does MMP2 Polyclonal Antibody come in?

MMP2 Polyclonal Antibody is available in 4 different pack sizes.

Is MMP2 Polyclonal Antibody in stock?

MMP2 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MMP2 Polyclonal Antibody?

MMP2 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for MMP2 Polyclonal Antibody?

Estimated delivery time for MMP2 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MMP2 Polyclonal Antibody?

The safety data sheet for MMP2 Polyclonal Antibody is available here: https://789.bio/eb/WDaXvP.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.