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Product details

NFκB-p105/p50 Polyclonal Antibody

Catalog number E-AB-32226-01

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Price for E-AB-32226-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-32226-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
NFkB is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. Activated NFkB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFkB has been associated with a number of inflammatory diseases while persistent inhibition of NFkB leads to inappropriate immune cell development or delayed cell growth. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. This antibody can bind both p105 and p50 isoforms of NFKB1.
Abbreviation
NFκB-p105/p50
UniProt
P19838
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human NFκB-p105/p50 around the non-phosphorylation site of Ser337.
Target
DKFZp686C01211; DNA binding factor KBF1; DNA binding factor KBF1 EBP1; DNA-binding factor KBF1; EBP 1; EBP-1; EBP1; KBF1; MGC54151; nf b; NF kappa B; NF kappaB; NF kappabeta; NF kB1; NFkappaB; NFKB 1; NFKB p105; NFKB p50; Nfkb1; NFKB1; Nuclear factor kappa B DNA binding subunit; Nuclear factor kappa-B; subunit 1; Nuclear factor NF kappa B p105 subunit; Nuclear factor NF kappa B p50 subunit; Nuclear factor NF-kappa-B p50 subunit; Nuclear factor of kappa light chain gene enhancer in B cells 1; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; p105; p50; p84/NF-kappa-B1 p98; Transcription factor NFKB1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Immunology; Signal Transduction
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
105kDa
Observed Molecular Weight
50,110kDa
Citation 01
https://journals.lww.com/cmj/Fulltext/9900/Human_papillomavirus,_tobacco,_and_poor_oral.47.aspx
Citation 02
https://www.sciencedirect.com/science/article/pii/S1567576917301893
Isotype
IgG

Frequently Asked Questions

What is the catalog number for NFκB-p105/p50 Polyclonal Antibody?

The catalog number for NFκB-p105/p50 Polyclonal Antibody is E-AB-32226.

What sizes are available for NFκB-p105/p50 Polyclonal Antibody?

NFκB-p105/p50 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does NFκB-p105/p50 Polyclonal Antibody come in?

NFκB-p105/p50 Polyclonal Antibody is available in 4 different pack sizes.

Is NFκB-p105/p50 Polyclonal Antibody in stock?

NFκB-p105/p50 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NFκB-p105/p50 Polyclonal Antibody?

NFκB-p105/p50 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for NFκB-p105/p50 Polyclonal Antibody?

Estimated delivery time for NFκB-p105/p50 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NFκB-p105/p50 Polyclonal Antibody?

The safety data sheet for NFκB-p105/p50 Polyclonal Antibody is available here: https://789.bio/eb/SqrvTS.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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