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Product details

RORC Polyclonal Antibody

Catalog number E-AB-32827-01

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Price for E-AB-32827-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-32827-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.RORC (RAR Related Orphan Receptor C) is a Protein Coding gene. Diseases associated with RORC include Immunodeficiency 42 and Anus Cancer. Among its related pathways are Circadian rythm related genes and Innate Immune System. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and steroid hormone receptor activity. An important paralog of this gene is RORA.
Abbreviation
RORγ
UniProt
P51449
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from the Internal region of human RORC
Target
IMD42; MGC129539; NR1F3; Nuclear receptor ROR gamma; Nuclear receptor ROR-gamma; Nuclear receptor RZR gamma; Nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; RAR related orphan nuclear receptor variant 2; RAR related orphan receptor C; RAR related orphan receptor C; isoform a; RAR related orphan receptor gamma; RAR-related orphan receptor C; Retinoic acid binding receptor gamma; Retinoid related orphan receptor gamma; Retinoid-related orphan receptor-gamma; Rorc; RORG; RORG; RZR GAMMA; RZRG; TOR
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Epigenetics and Nuclear Signaling; Signal Transduction
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
58kDa
Observed Molecular Weight
58kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for RORC Polyclonal Antibody?

The catalog number for RORC Polyclonal Antibody is E-AB-32827.

What sizes are available for RORC Polyclonal Antibody?

RORC Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does RORC Polyclonal Antibody come in?

RORC Polyclonal Antibody is available in 4 different pack sizes.

Is RORC Polyclonal Antibody in stock?

RORC Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RORC Polyclonal Antibody?

RORC Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for RORC Polyclonal Antibody?

Estimated delivery time for RORC Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for RORC Polyclonal Antibody?

The safety data sheet for RORC Polyclonal Antibody is available here: https://789.bio/eb/mTGy98.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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