SMG7 Polyclonal Antibody

Catalog number E-AB-32926-01

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Price for E-AB-32926-01

Size / count 20 µL

Specifications

Catalog number: E-AB-32926-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD) ; a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.SMG7 (SMG7, Nonsense Mediated MRNA Decay Factor) is a Protein Coding gene. Among its related pathways are Gene Expression and Viral mRNA Translation. GO annotations related to this gene include protein phosphatase 2A binding. An important paralog of this gene is SMG6.
Abbreviation: SMG7
UniProt: Q92540
Host: Rabbit
Reactivity: Human
Immunogen: Synthesized peptide derived from the Internal region of human SMG7
Target: Breast cancer-associated antigen SGA-56M; C1orf16; EST1 like protein C; EST1 telomerase component homolog C; EST1-like protein C; EST1C; ever shorter telomeres 1C; FLJ23717; hSMG-7; nonsense mediated mRNA decay factor (C. elegans) ; Protein SMG7; SGA56M; SMG 7; SMG-7 homolog; Smg7; SMG7
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC-p; IF
Field of Research: Epigenetics and Nuclear Signaling
Purification: Affinity purification
Concentration: 1mg/mL
Dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 127kDa
Observed Molecular Weight: 127kDa
Citation 01: https://academic.oup.com/nar/article-abstract/48/15/8626/5867419
Isotype: IgG

Frequently Asked Questions

What is the catalog number for SMG7 Polyclonal Antibody?

The catalog number for SMG7 Polyclonal Antibody is E-AB-32926.

What sizes are available for SMG7 Polyclonal Antibody?

SMG7 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does SMG7 Polyclonal Antibody come in?

SMG7 Polyclonal Antibody is available in 4 different pack sizes.

Is SMG7 Polyclonal Antibody in stock?

SMG7 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SMG7 Polyclonal Antibody?

SMG7 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for SMG7 Polyclonal Antibody?

Estimated delivery time for SMG7 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SMG7 Polyclonal Antibody?

The safety data sheet for SMG7 Polyclonal Antibody is available here: https://789.bio/eb/b1CSG0.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.