STAT1 Polyclonal Antibody

Catalog number E-AB-32977-01

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Price for E-AB-32977-01

Size / count 20 µL

Specifications

Catalog number: E-AB-32977-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Signal transducer and activator of transcription that mediates signaling by interferons (IFNs) . Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state.
Abbreviation: Stat1
UniProt: P42224
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Synthesized peptide derived from human Stat1 around the non-phosphorylation site of Ser727.
Target: Signal transducer and activator of transcription 1 91kD; CANDF7; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF 3; ISGF-3; OTTHUMP00000163552; OTTHUMP00000165046; OTTHUMP00000165047; OTTHUMP00000205845; Signal transducer and activator of transcription 1 91kDa; Signal transducer and activator of transcription 1; Signal transducer and activator of transcription 1;91kD; Signal transducer and activator of transcription 1-alpha/beta; STAT 1; Stat1; STAT1; STAT91; Transcription factor ISGF 3 components p91 p84; Transcription factor ISGF-3 components p91/p84
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC-p; IF
Field of Research: Cancer; Epigenetics and Nuclear Signaling; Signal Transduction
Purification: Affinity purification
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:50-1:200
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 87kDa
Observed Molecular Weight: 87kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for STAT1 Polyclonal Antibody?

The catalog number for STAT1 Polyclonal Antibody is E-AB-32977.

What sizes are available for STAT1 Polyclonal Antibody?

STAT1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does STAT1 Polyclonal Antibody come in?

STAT1 Polyclonal Antibody is available in 4 different pack sizes.

Is STAT1 Polyclonal Antibody in stock?

STAT1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures STAT1 Polyclonal Antibody?

STAT1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for STAT1 Polyclonal Antibody?

Estimated delivery time for STAT1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for STAT1 Polyclonal Antibody?

The safety data sheet for STAT1 Polyclonal Antibody is available here: https://789.bio/eb/9mHuX5.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.