TGFB1 Polyclonal Antibody

Catalog number E-AB-33090-01

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Price for E-AB-33090-01

Size / count 20 µL

Specifications

Catalog number: E-AB-33090-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells.
Abbreviation: TGFβ1
UniProt: P01137
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Synthesized peptide derived from the C-terminal region of human TGFβ1
Target: Cartilage-inducing factor; CED; Differentiation inhibiting factor; DPD1; LAP; Latency-associated peptide; Prepro transforming growth factor beta 1; TGF beta 1; TGF beta; TGF beta 1 protein; TGF-beta 1 protein; TGF-beta-1; TGF-beta-5; TGF-beta1; TGFB; Tgfb-1; tgfb1; TGFB1; TGFbeta; TGFbeta1; Transforming Growth Factor b1; Transforming Growth Factor beta 1; Transforming growth factor beta 1a; transforming growth factor beta-1; transforming growth factor; beta 1; Transforming Growth Factor-1
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC-p; IF
Field of Research: Cancer; Cardiovascular; Metabolism; Signal Transduction; Stem Cells
Purification: Affinity purification
Concentration: 1mg/mL
Dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 44kDa
Observed Molecular Weight: 44kDa
Citation 01: https://www.nature.com/articles/s41467-021-22305-x
Citation 02: https://www.ijbs.com/v19p0204.htm
Citation 03: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631930/
Citation 04: https://www.nature.com/articles/srep33856
Citation 05: https://www.sciencedirect.com/science/article/pii/S0014299922001923
Citation 06: https://www.frontiersin.org/articles/10.3389/fphys.2020.00403/full?report=reader
Citation 07: https://www.sciencedirect.com/science/article/pii/S0024320517304770
Citation 08: https://www.spandidos-publications.com/10.3892/mmr.2019.10744
Isotype: IgG

Frequently Asked Questions

What is the catalog number for TGFB1 Polyclonal Antibody?

The catalog number for TGFB1 Polyclonal Antibody is E-AB-33090.

What sizes are available for TGFB1 Polyclonal Antibody?

TGFB1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does TGFB1 Polyclonal Antibody come in?

TGFB1 Polyclonal Antibody is available in 4 different pack sizes.

Is TGFB1 Polyclonal Antibody in stock?

TGFB1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TGFB1 Polyclonal Antibody?

TGFB1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for TGFB1 Polyclonal Antibody?

Estimated delivery time for TGFB1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TGFB1 Polyclonal Antibody?

The safety data sheet for TGFB1 Polyclonal Antibody is available here: https://789.bio/eb/Te1ibH.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.