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Product details

TNF alpha Polyclonal Antibody

Catalog number E-AB-33121-01

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Price for E-AB-33121-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-33121-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
Abbreviation
TNF-α
UniProt
P01375
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the Internal region of human TNF-α
Target
APC1; APC1 protein; Cachectin; DIF; Differentiation inducing factor; Macrophage cytotoxic factor; Tnf; TNF superfamily; member 2; TNF; macrophage derived; TNF; monocyte derived; TNF-a; TNF-alpha; TNFA; TNFA; TNFSF2; Tumor necrosis factor alpha; Tumor necrosis factor; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor; Membrane Form; Tumor necrosis factor; soluble form
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Cardiovascular; Metabolism; Immunology; Signal Transduction
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
26kDa
Observed Molecular Weight
16kDa
Citation 01
https://www.nature.com/articles/s41590-022-01166-6
Citation 02
https://academic.oup.com/endo/advance-article-abstract/doi/10.1210/endocr/bqac203/6881427
Isotype
IgG

Frequently Asked Questions

What is the catalog number for TNF alpha Polyclonal Antibody?

The catalog number for TNF alpha Polyclonal Antibody is E-AB-33121.

What sizes are available for TNF alpha Polyclonal Antibody?

TNF alpha Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does TNF alpha Polyclonal Antibody come in?

TNF alpha Polyclonal Antibody is available in 4 different pack sizes.

Is TNF alpha Polyclonal Antibody in stock?

TNF alpha Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TNF alpha Polyclonal Antibody?

TNF alpha Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for TNF alpha Polyclonal Antibody?

Estimated delivery time for TNF alpha Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TNF alpha Polyclonal Antibody?

The safety data sheet for TNF alpha Polyclonal Antibody is available here: https://789.bio/eb/WzfTG8.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

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