Α-SMA Polyclonal Antibody

Specifications

Catalog number

E-AB-34268-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 (Actin, Alpha 2, Smooth Muscle, Aorta) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Moyamoya Disease 5. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include protein kinase binding. An important paralog of this gene is ACTG2. ACTA1 (Actin, Alpha 1, Skeletal Muscle) is a Protein Coding gene. Diseases associated with ACTA1 include Nemaline Myopathy 3, Autosomal Dominant Or Recessive and Myopathy, Congenital, With Fiber-Type Disproportion. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include structural constituent of cytoskeleton and myosin binding. An important paralog of this gene is ACTC1. ACTG2 (Actin, Gamma 2, Smooth Muscle, Enteric) is a Protein Coding gene. Diseases associated with ACTG2 include Visceral Myopathy and Chronic Intestinal Pseudoobstruction. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. An important paralog of this gene is ACTA2.

Abbreviation

Α-SMA

UniProt

P62736, P68133, P63267

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from α-SMA

Target

A actin; AAT6; ACTA; ACTA2; Actin alpha 2 smooth muscle aorta; Actin aortic smooth muscle; Actin; aortic smooth muscle; ACTSA; ACTVS; Alpha 2 actin; Alpha actin 2; Alpha cardiac actin; alpha sma; Alpha-actin-2; Cell growth inhibiting gene 46 protein; Cell growth-inhibiting gene 46 protein; GIG46; Growth inhibiting gene 46; MYMY5; ACTC; ACTC; ACTC1; Actin alpha cardiac muscle 1; Actin; alpha cardiac muscle 1; Alpha-cardiac actin; ASD5; CMD1R; CMH11; LVNC4; a actin; Actin alpha skeletal muscle; Actin; actin; alpha 1; skeletal muscle 1; actin; alpha 1; skeletal muscle; Actin; alpha skeletal muscle; actina; actine; ACTS; aktin; Alpha Actin 1; ; ASMA; CFTD; CFTD1; CFTDM; MPFD; NEM1; NEM2; NEM3; nemaline myopathy type 3

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC-p; IF

Field of Research

Cancer; Cardiovascular; Developmental Biology; Signal Transduction; Stem Cells

Purification

Affinity purification

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC 1:50-300; IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

42kDa

Observed Molecular Weight

42kDa

Citation 01

https://www.nature.com/articles/s41467-022-30464-8

Citation 02

https://www.sciencedirect.com/science/article/pii/S0141813022026228

Citation 03

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068511/

Citation 04

https://www.sciencedirect.com/science/article/pii/S002432052200577X

Citation 05

https://www.sciencedirect.com/science/article/pii/S0024320522009560

Citation 06

https://www.mdpi.com/2150366

Citation 07

https://www.mdpi.com/2073-4409/8/11/1435

Citation 08

https://onlinelibrary.wiley.com/doi/abs/10.1002/cam4.5081

Citation 09

https://www.mdpi.com/1587758

Citation 10

https://www.sciencedirect.com/science/article/pii/S0022030223000644

Citation 11

https://www.tandfonline.com/doi/abs/10.1080/21655979.2021.1954580

Citation 12

https://jpet.aspetjournals.org/content/364/3/399.abstract

Isotype

IgG