SNCA Polyclonal Antibody

Catalog number E-AB-36111-01

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Price for E-AB-36111-01

Size / count 20 µL

Specifications

Catalog number: E-AB-36111-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
Abbreviation: Synuclein-α
UniProt: P37840
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Synthesized peptide derived from the Internal region of human Synuclein-α.
Target: Alpha synuclein; Alpha-synuclein; Alpha-synuclein; isoform NACP140; alphaSYN; MGC105443; MGC110988; MGC127560; MGC64356; NACP; Non A beta component of AD amyloid; Non A4 component of amyloid; Non A4 component of amyloid precursor; Non-A beta component of AD amyloid; Non-A-beta component of alzheimers disease amyloid; precursor of; Non-A4 component of amyloid precursor; Non-A4 component of amyloid; precursor of; OTTHUMP00000218549; OTTHUMP00000218551; OTTHUMP00000218552; OTTHUMP00000218553; OTTHUMP00000218554; PARK 1; PARK 4; PARK1; PARK4; Parkinson disease (autosomal dominant; Lewy body) 4; Parkinson disease familial 1; SNCA; Snca synuclein; alpha (non A4 component of amyloid precursor) ; SYN; Synuclein alpha; Synuclein alpha 140; Synuclein; alpha (non A4 component of amyloid precursor) ; SYUA
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC-p
Field of Research: Cancer; Neuroscience
Purification: Affinity purification
Concentration: 1mg/mL
Dilution: WB 1:500-1:2000; IHC 1:100-1:300
Buffer: PBS with 0.02% sodium azide,0.5% protective protein and 50% glycerol pH 7.4.
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 14kDa
Observed Molecular Weight: 15kDa
Citation 01: https://link.springer.com/article/10.1007/s12640-023-00637-4
Citation 02: https://www.sciencedirect.com/science/article/pii/S0006899322001822
Isotype: IgG

Frequently Asked Questions

What is the catalog number for SNCA Polyclonal Antibody?

The catalog number for SNCA Polyclonal Antibody is E-AB-36111.

What sizes are available for SNCA Polyclonal Antibody?

SNCA Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does SNCA Polyclonal Antibody come in?

SNCA Polyclonal Antibody is available in 4 different pack sizes.

Is SNCA Polyclonal Antibody in stock?

SNCA Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SNCA Polyclonal Antibody?

SNCA Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for SNCA Polyclonal Antibody?

Estimated delivery time for SNCA Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SNCA Polyclonal Antibody?

The safety data sheet for SNCA Polyclonal Antibody is available here: https://789.bio/eb/9efnTK.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.