Product details

AKT1 Polyclonal Antibody

Catalog number E-AB-40032-01

Discontinued

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Price for E-AB-40032-01

Size / count 25 µL

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Specifications

Catalog number: E-AB-40032-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.
Abbreviation: AKT1
UniProt: P31750
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant Mouse RAC-alpha serine/threonine-protein kinase protein
Target: AKT 1; AKT; AKT1; AKT1; MGC99656; PKB; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha; RAC; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Epigenetics and Nuclear Signaling; Metabolism; Signal transduction
Purification: Antigen Affinity Purification
Concentration: 1 mg/mL
Dilution: IHC 1:50-1:100
Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for AKT1 Polyclonal Antibody?

The catalog number for AKT1 Polyclonal Antibody is E-AB-40032.

What sizes are available for AKT1 Polyclonal Antibody?

AKT1 Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does AKT1 Polyclonal Antibody come in?

AKT1 Polyclonal Antibody is available in 2 different pack sizes.

Is AKT1 Polyclonal Antibody in stock?

AKT1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AKT1 Polyclonal Antibody?

AKT1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for AKT1 Polyclonal Antibody?

Estimated delivery time for AKT1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for AKT1 Polyclonal Antibody?

The safety data sheet for AKT1 Polyclonal Antibody is available here: https://789.bio/eb/98SSO8.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.