Product details

Aβ40 Polyclonal Antibody

Catalog number E-AB-40070-01

Discontinued

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Price for E-AB-40070-01

Size / count 25 µL

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Specifications

Catalog number: E-AB-40070-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Aβ derives from APP via proteolytic cleavage by proteases called α-, β- and γ-secretase. The α-secretase cleavage precludes the formation of Aβ, while the β- and γ-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein (APP), encoded by APP gene which locate on human chromosome 21q, is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain, kidney, heart and spleen, but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 (AD1) . This antibody can recogniaze the N-terminus of human APP: Soluble APP-alpha and Soluble APP-beta.
Abbreviation: Aβ40
UniProt: P12023
Host: Rabbit
Reactivity: Mouse; Rat
Immunogen: Recombinant Mouse Beta-amyloid 40 protein
Target: A4 amyloid protein; A4; AAA; ABETA; ABPP; AD1; AICD-50; AICD-57; AICD-59; AID (50) ; AID (57) ; AID (59) ; Alzheimer disease amyloid protein; Amyloid beta (A4) precursor protein; Amyloid beta A4 protein; Amyloid beta protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; APP; APPI; Beta amyloid peptide; Beta-amyloid precursor protein; Beta-APP40; Beta-APP42; C31; Cerebral vascular amyloid peptide; CTFgamma; CVAP; Gamma-CTF (50) ; Gamma-CTF (57) ; Gamma-CTF (59) ; peptidase nexin II; PN 2; PN II; PN-II; PN2; PreA4; Protease nexin II; Protease nexin-II; S-APP-alpha; S-APP-beta
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Neuroscience
Purification: Antigen Affinity Purification
Concentration: 1 mg/mL
Dilution: IHC 1:50-1:100
Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Aβ40 Polyclonal Antibody?

The catalog number for Aβ40 Polyclonal Antibody is E-AB-40070.

What sizes are available for Aβ40 Polyclonal Antibody?

Aβ40 Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does Aβ40 Polyclonal Antibody come in?

Aβ40 Polyclonal Antibody is available in 2 different pack sizes.

Is Aβ40 Polyclonal Antibody in stock?

Aβ40 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Aβ40 Polyclonal Antibody?

Aβ40 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Aβ40 Polyclonal Antibody?

Estimated delivery time for Aβ40 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Aβ40 Polyclonal Antibody?

The safety data sheet for Aβ40 Polyclonal Antibody is available here: https://789.bio/eb/yLy94G.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.