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Product details

Lamin B1 Polyclonal Antibody

Catalog number E-AB-40257-01

Discontinued

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Price for E-AB-40257-01

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Size / count 25 µL

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Specifications

Catalog number
E-AB-40257-01
Size / count
25 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD) .
Abbreviation
Lamin B1
UniProt
P70615
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Rat Lamin-B1 protein expressed by E.coli
Target
ADLD; lamin B1; Lamin-B1; LMN; LMN2; LMNB; Lmnb1; LMNB1; MGC111419; OTTHUMP00000159218
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Cancer; Cell Biology; Signal Transduction; Tags and Cell Markers
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:250-1:500; IHC 1:200-1:600
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
67 kDa
Observed Molecular Weight
72 kDa
Citation 01
https://link.springer.com/article/10.1007/s12035-022-02923-2
Isotype
IgG

Frequently Asked Questions

What is the catalog number for Lamin B1 Polyclonal Antibody?

The catalog number for Lamin B1 Polyclonal Antibody is E-AB-40257.

What sizes are available for Lamin B1 Polyclonal Antibody?

Lamin B1 Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does Lamin B1 Polyclonal Antibody come in?

Lamin B1 Polyclonal Antibody is available in 2 different pack sizes.

Is Lamin B1 Polyclonal Antibody in stock?

Lamin B1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Lamin B1 Polyclonal Antibody?

Lamin B1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Lamin B1 Polyclonal Antibody?

Estimated delivery time for Lamin B1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Lamin B1 Polyclonal Antibody?

The safety data sheet for Lamin B1 Polyclonal Antibody is available here: https://789.bio/eb/OqnH0K.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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