Product details

GCK Polyclonal Antibody

Catalog number E-AB-40270-01

Discontinued

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Price for E-AB-40270-01

Size / count 25 µL

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Specifications

Catalog number: E-AB-40270-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI) .
Abbreviation: GCK
UniProt: P52792
Host: Rabbit
Reactivity: Human; Mouse
Immunogen: Recombinant Mouse Glucokinase protein
Target: ATP:D-hexose 6-phosphotransferase; FGQTL3; GCK; GK; GLK; Glucokinase; Hexokinase D pancreatic isozyme; Hexokinase type IV; Hexokinase-4; Hexokinase-D; HHF3; HK IV; HK4; HKIV; HXK4; HXKP; LGLK; MODY2
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC; IF
Field of Research: Cancer; Metabolism; Signal Transduction
Purification: Antigen Affinity Purification
Concentration: 1 mg/mL
Dilution: WB 1:1000-1:2000; IHC 1:100-1:200; IF 1:100-1:400
Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 52 kDa
Observed Molecular Weight: 52kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for GCK Polyclonal Antibody?

The catalog number for GCK Polyclonal Antibody is E-AB-40270.

What sizes are available for GCK Polyclonal Antibody?

GCK Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does GCK Polyclonal Antibody come in?

GCK Polyclonal Antibody is available in 2 different pack sizes.

Is GCK Polyclonal Antibody in stock?

GCK Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GCK Polyclonal Antibody?

GCK Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for GCK Polyclonal Antibody?

Estimated delivery time for GCK Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GCK Polyclonal Antibody?

The safety data sheet for GCK Polyclonal Antibody is available here: https://789.bio/eb/PafPS0.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.