BRCA2 Polyclonal Antibody — image 1 of 7

Product details

BRCA2 Polyclonal Antibody

Catalog number E-AB-40288-01

Discontinued

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Price for E-AB-40288-01

Size / count 25 µL

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Specifications

Catalog number: E-AB-40288-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.
Abbreviation: BRCA2
UniProt: P51587
Host: Rabbit
Reactivity: Human; Rat
Immunogen: Recombinant Human Breast cancer type 2 susceptibility protein
Target: BRCA 2; BRCC 2; Breast and ovarian cancer susceptibility gene early onset antibody; BROVCA2; FACD; FAD 1; FANCB; GLM3
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC; IF
Field of Research: Cancer; Epigenetics and Nuclear Signaling
Purification: Antigen Affinity Purification
Concentration: 1 mg/mL
Dilution: WB 1:1000-1:3000; IHC 1:100-1:200; IF 1:100-1:400
Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 384 kDa
Observed Molecular Weight: 384 kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for BRCA2 Polyclonal Antibody?

The catalog number for BRCA2 Polyclonal Antibody is E-AB-40288.

What sizes are available for BRCA2 Polyclonal Antibody?

BRCA2 Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does BRCA2 Polyclonal Antibody come in?

BRCA2 Polyclonal Antibody is available in 2 different pack sizes.

Is BRCA2 Polyclonal Antibody in stock?

BRCA2 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BRCA2 Polyclonal Antibody?

BRCA2 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for BRCA2 Polyclonal Antibody?

Estimated delivery time for BRCA2 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BRCA2 Polyclonal Antibody?

The safety data sheet for BRCA2 Polyclonal Antibody is available here: https://789.bio/eb/4iPyj1.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.