PCNA Polyclonal Antibody

Catalog number E-AB-40489-01

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Price for E-AB-40489-01

Size / count 25 µL

Specifications

Catalog number: E-AB-40489-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Proliferating Cell Nuclear Antigen, commonly known as PCNA, is a protein that acts as a processivity factor for DNA polymerase δ in eukaryotic cells. This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. PCNA induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. It has to be loaded onto DNA in order to be able to stimulate APEX2. PCNA protein is highly conserved during evolution; the deduced amino acid sequences of rat and human differ by only 4 of 261 amino acids. PCNA has been used as loading control for proliferating cells.
Abbreviation: PCNA
UniProt: P12004
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of Human Proliferating cell nuclear antigen
Target: ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; PCNA; Pcna/cyclin; PCNA; PCNAR; Polymerase delta accessory protein; Proliferating cell nuclear antigen
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB
Field of Research: Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Tags and Cell Markers
Purification: Antigen Affinity Purification
Concentration: 1 mg/mL
Dilution: WB 1:3000-1:7000
Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 28 kDa
Observed Molecular Weight: 35 kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for PCNA Polyclonal Antibody?

The catalog number for PCNA Polyclonal Antibody is E-AB-40489.

What sizes are available for PCNA Polyclonal Antibody?

PCNA Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does PCNA Polyclonal Antibody come in?

PCNA Polyclonal Antibody is available in 2 different pack sizes.

Is PCNA Polyclonal Antibody in stock?

PCNA Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PCNA Polyclonal Antibody?

PCNA Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for PCNA Polyclonal Antibody?

Estimated delivery time for PCNA Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PCNA Polyclonal Antibody?

The safety data sheet for PCNA Polyclonal Antibody is available here: https://789.bio/eb/aLibv1.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.