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Product details

CXCL12/SDF1 Polyclonal Antibody

Catalog number E-AB-40578-01

Discontinued

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Price for E-AB-40578-01

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Size / count 25 µL

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Specifications

Catalog number
E-AB-40578-01
Size / count
25 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
The stromal cell derived factor 1 (SDF1/CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1/CXCL12 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1/CXCL12 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1/CXCL12 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1/CXCL12 isoforms (SDF1/CXCL12α and SDF1/CXCL12β) that have different properties and biological activities. Additional isoforms of SDF1/CXCL12 have been reported.
Abbreviation
CXCL12
UniProt
Q9QZD1
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Rat CXCL12 protein expressed by E.coli.
Target
Cxcl12; SDF-1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Immunology; Microbiology; Cardiovascular
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:2000-4000
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
10kDa
Observed Molecular Weight
10kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for CXCL12/SDF1 Polyclonal Antibody?

The catalog number for CXCL12/SDF1 Polyclonal Antibody is E-AB-40578.

What sizes are available for CXCL12/SDF1 Polyclonal Antibody?

CXCL12/SDF1 Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does CXCL12/SDF1 Polyclonal Antibody come in?

CXCL12/SDF1 Polyclonal Antibody is available in 2 different pack sizes.

Is CXCL12/SDF1 Polyclonal Antibody in stock?

CXCL12/SDF1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CXCL12/SDF1 Polyclonal Antibody?

CXCL12/SDF1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CXCL12/SDF1 Polyclonal Antibody?

Estimated delivery time for CXCL12/SDF1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CXCL12/SDF1 Polyclonal Antibody?

The safety data sheet for CXCL12/SDF1 Polyclonal Antibody is available here: https://789.bio/eb/KOSmj9.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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