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Product details

DnaseIPolyclonal Antibody

Catalog number E-AB-40592-01

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Price for E-AB-40592-01

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Size / count 25 µL

Specifications

Catalog number
E-AB-40592-01
Size / count
25 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Deoxyribonuclease I (DNase I) is an endonuclease which is secreted to cleave DNA in the extracellular space down to an average of tetranucleotides with 5′ monophosphate and 3′ hydroxyl DNA ends . Both single-stranded DNA and double-stranded DNA are degraded by Dnase I. This nuclease appears to account for the major nucleolytic activity on DNA in serum and is responsible for the degradation of the majority of circulating DNA derived from apoptotic and necrotic cell death and from neutrophil extracellular traps. In addition to its role in the serum, it has been proposed as one of the deoxyribonucleases responsible for DNA fragmentation in the process of apoptosis.
Abbreviation
DnaseI
UniProt
P24855
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human DnaseI protein expressed by E.coli.
Target
Deoxyribonuclease-1; DNASE1; DNL1; DRNI
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Metabolism
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:1000-2000
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
31kDa
Observed Molecular Weight
31kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for DnaseIPolyclonal Antibody?

The catalog number for DnaseIPolyclonal Antibody is E-AB-40592.

What sizes are available for DnaseIPolyclonal Antibody?

DnaseIPolyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does DnaseIPolyclonal Antibody come in?

DnaseIPolyclonal Antibody is available in 2 different pack sizes.

Is DnaseIPolyclonal Antibody in stock?

DnaseIPolyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DnaseIPolyclonal Antibody?

DnaseIPolyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for DnaseIPolyclonal Antibody?

Estimated delivery time for DnaseIPolyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for DnaseIPolyclonal Antibody?

The safety data sheet for DnaseIPolyclonal Antibody is available here: https://789.bio/eb/4ifrXH.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

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