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Product details

NF2 / Merlin Polyclonal Antibody

Catalog number E-AB-40642-01

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Price for E-AB-40642-01

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Size / count 25 µL

Specifications

Catalog number
E-AB-40642-01
Size / count
25 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.
Abbreviation
NF2
UniProt
P35240
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human NF2 protein expressed by E.coli.
Target
ACN; BANF; Merlin; Neurofibromin 2; neurofibromin 2 (merlin) ; NF2; SCH; Schwannomerlin; Schwannomin
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Neuroscience; Signal Transduction
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
70 kDa
Observed Molecular Weight
66-70 kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for NF2 / Merlin Polyclonal Antibody?

The catalog number for NF2 / Merlin Polyclonal Antibody is E-AB-40642.

What sizes are available for NF2 / Merlin Polyclonal Antibody?

NF2 / Merlin Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does NF2 / Merlin Polyclonal Antibody come in?

NF2 / Merlin Polyclonal Antibody is available in 2 different pack sizes.

Is NF2 / Merlin Polyclonal Antibody in stock?

NF2 / Merlin Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NF2 / Merlin Polyclonal Antibody?

NF2 / Merlin Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for NF2 / Merlin Polyclonal Antibody?

Estimated delivery time for NF2 / Merlin Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NF2 / Merlin Polyclonal Antibody?

The safety data sheet for NF2 / Merlin Polyclonal Antibody is available here: https://789.bio/eb/4Sqb1S.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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