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Product details

IL4R Polyclonal Antibody

Catalog number E-AB-52020-01

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Price for E-AB-52020-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-52020-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
Abbreviation
IL4R
UniProt
P24394
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human IL4R
Target
CD124; IL 4R alpha; IL-4 receptor subunit alpha; IL-4-binding protein; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; IL4-BP; Il4r; IL4R nirs variant 1; IL4RA; IL4RA; Interleukin 4 receptor alpha chain; Interleukin 4 receptor; sIL4Ralpha/prot; Soluble IL-4 receptor subunit alpha; Soluble IL-4R-alpha; Soluble interleukin-4 receptor subunit alpha
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Immunology
Purification
Antigen affinity purification
Concentration
1.26 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for IL4R Polyclonal Antibody?

The catalog number for IL4R Polyclonal Antibody is E-AB-52020.

What sizes are available for IL4R Polyclonal Antibody?

IL4R Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does IL4R Polyclonal Antibody come in?

IL4R Polyclonal Antibody is available in 4 different pack sizes.

Is IL4R Polyclonal Antibody in stock?

IL4R Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures IL4R Polyclonal Antibody?

IL4R Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for IL4R Polyclonal Antibody?

Estimated delivery time for IL4R Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for IL4R Polyclonal Antibody?

The safety data sheet for IL4R Polyclonal Antibody is available here: https://789.bio/eb/ev5irL.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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