GRIA2 Polyclonal Antibody

Catalog number E-AB-52034-01

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Price for E-AB-52034-01

Size / count 20 µL

Specifications

Catalog number: E-AB-52034-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca (2+) . Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
Abbreviation: GRIA2
UniProt: P42262
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Synthetic peptide of human GRIA2
Target: AMPA 2; AMPA selective glutamate receptor 2; AMPA-selective glutamate receptor 2; AMPA2; GluA2; GLUR 2; GLUR B; GluR K2; GluR-2; GluR-B; GluR-K2; GLUR2; GLURB; Glutamate receptor 2; Glutamate receptor ionotropic AMPA 2; Glutamate receptor ionotropic; Gria2; GRIA2; HBGR2
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Neuroscience
Purification: Antigen affinity purification
Concentration: 1.08 mg/mL
Dilution: IHC 1:40-1:200
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for GRIA2 Polyclonal Antibody?

The catalog number for GRIA2 Polyclonal Antibody is E-AB-52034.

What sizes are available for GRIA2 Polyclonal Antibody?

GRIA2 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does GRIA2 Polyclonal Antibody come in?

GRIA2 Polyclonal Antibody is available in 4 different pack sizes.

Is GRIA2 Polyclonal Antibody in stock?

GRIA2 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GRIA2 Polyclonal Antibody?

GRIA2 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for GRIA2 Polyclonal Antibody?

Estimated delivery time for GRIA2 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GRIA2 Polyclonal Antibody?

The safety data sheet for GRIA2 Polyclonal Antibody is available here: https://789.bio/eb/vrTOi1.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.