KCNN1 Polyclonal Antibody

Specifications

Catalog number

E-AB-52082-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes.

Abbreviation

KCNN1

UniProt

Q92952

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide of human KCNN1

Target

HSK1 ; KCa2.1; KCNN 1; Kcnn1; KCNN1; Potassium intermediate/small conductance calcium activated channel subfamily N member 1; SK; SK1; SKCa 1; SKCa1; Small conductance calcium activated potassium channel protein 1; Small conductance calcium-activated potassium channel protein 1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Neuroscience

Purification

Antigen affinity purification

Concentration

1.56 mg/mL

Dilution

IHC 1:50-1:300

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG