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Product details

SHTN1 Polyclonal Antibody

Catalog number E-AB-52104-01

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Price for E-AB-52104-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-52104-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Involved in the generation of internal asymmetric signals required for neuronal polarization and neurite outgrowth. Mediates netrin-1-induced F-actin-substrate coupling or 'clutch engagement' within the axon growth cone through activation of CDC42, RAC1 and PAK1-dependent signaling pathway, thereby converting the F-actin retrograde flow into traction forces, concomitantly with filopodium extension and axon outgrowth. Plays a role in cytoskeletal organization by regulating the subcellular localization of phosphoinositide 3-kinase (PI3K) activity at the axonal growth cone. Plays also a role in regenerative neurite outgrowth. In the developing cortex, cooperates with KIF20B to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in the accumulation of phosphatidylinositol 3,4,5-trisphosphate (PIP3) in the growth cone of primary hippocampal neurons.
Abbreviation
SHTN1
UniProt
A0MZ66
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human SHTN1
Target
DKFZp686A0439; hypothetical protein FLJ11122; Kiaa1598; MGC40476; Putative uncharacterized protein KIAA1598; Shootin 1; Shootin-1; SHOT1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Neuroscience
Purification
Antigen affinity purification
Concentration
0.48 mg/mL
Dilution
IHC 1:50-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for SHTN1 Polyclonal Antibody?

The catalog number for SHTN1 Polyclonal Antibody is E-AB-52104.

What sizes are available for SHTN1 Polyclonal Antibody?

SHTN1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does SHTN1 Polyclonal Antibody come in?

SHTN1 Polyclonal Antibody is available in 4 different pack sizes.

Is SHTN1 Polyclonal Antibody in stock?

SHTN1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SHTN1 Polyclonal Antibody?

SHTN1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for SHTN1 Polyclonal Antibody?

Estimated delivery time for SHTN1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SHTN1 Polyclonal Antibody?

The safety data sheet for SHTN1 Polyclonal Antibody is available here: https://789.bio/eb/fTqTa9.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

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