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Product details

NR0B2 Polyclonal Antibody

Catalog number E-AB-52169-01

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Price for E-AB-52169-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-52169-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function.
Abbreviation
NR0B2
UniProt
Q15466
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human NR0B2
Target
NR0B2; NR0B2; Nr0b2a; Nuclear receptor subfamily 0 group B member 2; Nuclear receptor subfamily 0; group B; member 2a; Orphan nuclear receptor SHP; SHP; SHP-1; Shp1; Small heterodimer partner
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Metabolism; Signal transduction
Purification
Antigen affinity purification
Concentration
0.6 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for NR0B2 Polyclonal Antibody?

The catalog number for NR0B2 Polyclonal Antibody is E-AB-52169.

What sizes are available for NR0B2 Polyclonal Antibody?

NR0B2 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does NR0B2 Polyclonal Antibody come in?

NR0B2 Polyclonal Antibody is available in 4 different pack sizes.

Is NR0B2 Polyclonal Antibody in stock?

NR0B2 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NR0B2 Polyclonal Antibody?

NR0B2 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for NR0B2 Polyclonal Antibody?

Estimated delivery time for NR0B2 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NR0B2 Polyclonal Antibody?

The safety data sheet for NR0B2 Polyclonal Antibody is available here: https://789.bio/eb/GujT08.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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