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Product details

PRKAR2A Polyclonal Antibody

Catalog number E-AB-52196-01

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Price for E-AB-52196-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-52196-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER) .
Abbreviation
PRKAR2A
UniProt
P13861
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human PRKAR2A
Target
CAMP dependent protein kinase regulatory subunit alpha 2; cAMP dependent protein kinase regulatory subunit RII alpha; cAMP dependent protein kinase type II alpha regulatory chain; cAMP dependent protein kinase type II alpha regulatory subunit; cAMP-dependent protein kinase type II-alpha regulatory subunit; KAP2; KAP2; MGC3606; PKR 2; PKR2; PRKA R2; PRKAR 2; PRKAR2; PRKAR2A; Protein kinase A RII alpha subunit; Protein kinase cAMP dependent regulatory type II alpha
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Metabolism; Signal Transduction
Purification
Antigen affinity purification
Concentration
0.8 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:35-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

Frequently Asked Questions

What is the catalog number for PRKAR2A Polyclonal Antibody?

The catalog number for PRKAR2A Polyclonal Antibody is E-AB-52196.

What sizes are available for PRKAR2A Polyclonal Antibody?

PRKAR2A Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does PRKAR2A Polyclonal Antibody come in?

PRKAR2A Polyclonal Antibody is available in 4 different pack sizes.

Is PRKAR2A Polyclonal Antibody in stock?

PRKAR2A Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PRKAR2A Polyclonal Antibody?

PRKAR2A Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for PRKAR2A Polyclonal Antibody?

Estimated delivery time for PRKAR2A Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PRKAR2A Polyclonal Antibody?

The safety data sheet for PRKAR2A Polyclonal Antibody is available here: https://789.bio/eb/D84mPS.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

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