ALKBH8 Polyclonal Antibody

Catalog number E-AB-52350-01

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Price for E-AB-52350-01

Size / count 20 µL

Specifications

Catalog number: E-AB-52350-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: ALKBH8 (alkylated DNA repair protein AlkB homolog 8) is a 664 amino acid protein that is encoded by a gene located on chromosome 11. ALKBH8 contains one RRM (RNA recognition motif) domain and belongs to the AlkB family of proteins. ALKBH8 is one of many homologs of the Escherichia coli protein AlkB. AlkB functions to protect DNA and RNA against damage from environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzyme acts by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate and molecular oxygen as the oxidizing agent. Three isoforms exist for ALKBH8 due alternative splicing of the gene.
Abbreviation: ALKBH8
UniProt: Q96BT7
Host: Rabbit
Reactivity: Human
Immunogen: Full length fusion protein
Target: 4930562C03Rik;8030431D03Rik;9430088N01Rik; ABH8; alkB alkylation repair homolog 8 (E. coli) ; alkB alkylation repair homolog 8; AlkB homologue 8; ALKB8; ALKBH8; Alkylated DNA repair protein alkB homolog 8; FLJ38204; MGC10235; OTTHUMP00000211286; OTTHUMP00000211287; Probable alpha-ketoglutarate-dependent dioxygenase ABH8; RGD1304687; S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8; tRNA (carboxymethyluridine (34) -5-O) -methyltransferase ABH8
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Epigenetics and Nuclear Signaling
Purification: Antigen affinity purification
Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:25-1:100
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 75 kDa
Observed Molecular Weight: Refer to figures
Isotype: IgG

Frequently Asked Questions

What is the catalog number for ALKBH8 Polyclonal Antibody?

The catalog number for ALKBH8 Polyclonal Antibody is E-AB-52350.

What sizes are available for ALKBH8 Polyclonal Antibody?

ALKBH8 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does ALKBH8 Polyclonal Antibody come in?

ALKBH8 Polyclonal Antibody is available in 4 different pack sizes.

Is ALKBH8 Polyclonal Antibody in stock?

ALKBH8 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ALKBH8 Polyclonal Antibody?

ALKBH8 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for ALKBH8 Polyclonal Antibody?

Estimated delivery time for ALKBH8 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ALKBH8 Polyclonal Antibody?

The safety data sheet for ALKBH8 Polyclonal Antibody is available here: https://789.bio/eb/nTOuH4.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.