GCLC Polyclonal Antibody

Catalog number E-AB-52359-01

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Price for E-AB-52359-01

Size / count 20 µL

Specifications

Catalog number: E-AB-52359-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
Abbreviation: GCLC
UniProt: P48506
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Fusion protein of human GCLC
Target: EC 6.3.2.2; Gamma ECS; Gamma glutamylcysteine synthetase; Gamma-ECS; Gamma-glutamylcysteine synthetase; GCL; Gclc; GCS; GCS heavy chain; GLCL; GLCLC; Glutamate cysteine ligase catalytic subunit; Glutamate--cysteine ligase catalytic subunit; GSH1
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Cell Biology; Metabolism; Signal Transduction
Purification: Antigen affinity purification
Concentration: 0.8 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:25-1:100
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 73 kDa
Observed Molecular Weight: Refer to figures
Citation 01: https://www.sciencedirect.com/science/article/pii/S2213231721002007
Citation 02: https://www.mdpi.com/1170076
Isotype: IgG

Frequently Asked Questions

What is the catalog number for GCLC Polyclonal Antibody?

The catalog number for GCLC Polyclonal Antibody is E-AB-52359.

What sizes are available for GCLC Polyclonal Antibody?

GCLC Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does GCLC Polyclonal Antibody come in?

GCLC Polyclonal Antibody is available in 4 different pack sizes.

Is GCLC Polyclonal Antibody in stock?

GCLC Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GCLC Polyclonal Antibody?

GCLC Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for GCLC Polyclonal Antibody?

Estimated delivery time for GCLC Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GCLC Polyclonal Antibody?

The safety data sheet for GCLC Polyclonal Antibody is available here: https://789.bio/eb/qPqvfL.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.