ZNF281 Polyclonal Antibody

Specifications

Catalog number

E-AB-52368-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Krüppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase) . In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR.

Abbreviation

ZNF281

UniProt

Q9Y2X9

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Fusion protein of human ZNF281

Target

GC box binding zinc finger protein 1; GC-box-binding zinc finger protein 1; GZP1; Transcription factor ZBP-99; ZBP 99; ZBP99; zfp281; Zinc finger DNA binding protein 99; Zinc finger DNA-binding protein 99; Zinc finger protein 281; ZN281; ZNF281; ZNP 99; ZNP 99 transcription factor; ZNP99

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Epigenetics and Nuclear Signaling; Developmental Biology; Stem Cells

Purification

Antigen affinity purification

Concentration

1.2 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:60-1:450

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

97 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG