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Product details

CEP57 Polyclonal Antibody

Catalog number E-AB-52539-01

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Price for E-AB-52539-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-52539-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Abbreviation
CEP57
UniProt
Q86XR8
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Full length fusion protein
Target
Centrosomal protein 57kDa; Centrosomal protein of 57 kDa; Cep57; Cep57 protein; CEP57; FGF2 interacting protein; FGF2-interacting protein; KIAA0092; MVA2; PIG8; Proliferation inducing protein 8; Testis specific protein 57; Testis-specific protein 57; Translokin; TSP57
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal transduction; Stem cells
Purification
Antigen affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
57 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

Frequently Asked Questions

What is the catalog number for CEP57 Polyclonal Antibody?

The catalog number for CEP57 Polyclonal Antibody is E-AB-52539.

What sizes are available for CEP57 Polyclonal Antibody?

CEP57 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does CEP57 Polyclonal Antibody come in?

CEP57 Polyclonal Antibody is available in 4 different pack sizes.

Is CEP57 Polyclonal Antibody in stock?

CEP57 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CEP57 Polyclonal Antibody?

CEP57 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CEP57 Polyclonal Antibody?

Estimated delivery time for CEP57 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CEP57 Polyclonal Antibody?

The safety data sheet for CEP57 Polyclonal Antibody is available here: https://789.bio/eb/m58SqT.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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