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Product details

POLH Polyclonal Antibody

Catalog number E-AB-52741-01

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Price for E-AB-52741-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-52741-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.
Abbreviation
POLH
UniProt
Q9Y253
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human POLH
Target
DNA polymerase eta; FLJ16395; FLJ21978; Polh; POLH; polymerase DNA directed eta; RAD30; RAD30 homolog A; RAD30A; Xeroderma pigmentosum variant type protein; XP V; XPV
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Antigen affinity purification
Concentration
0.78 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
78 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

Frequently Asked Questions

What is the catalog number for POLH Polyclonal Antibody?

The catalog number for POLH Polyclonal Antibody is E-AB-52741.

What sizes are available for POLH Polyclonal Antibody?

POLH Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does POLH Polyclonal Antibody come in?

POLH Polyclonal Antibody is available in 4 different pack sizes.

Is POLH Polyclonal Antibody in stock?

POLH Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures POLH Polyclonal Antibody?

POLH Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for POLH Polyclonal Antibody?

Estimated delivery time for POLH Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for POLH Polyclonal Antibody?

The safety data sheet for POLH Polyclonal Antibody is available here: https://789.bio/eb/fzD0OK.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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