EIF3C Polyclonal Antibody

Catalog number E-AB-52777-01

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Price for E-AB-52777-01

Size / count 20 µL

Specifications

Catalog number: E-AB-52777-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815) . The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632) . The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773) .
Abbreviation: EIF3C
UniProt: Q99613
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Fusion protein of human EIF3C
Target: Cell migration inducing protein 17; eIF 3c; eIF3 p110; eIF3-p110; eIF3c; EIF3C; EIF3CL; EIF3S8; EIF3S8 protein; Eukaryotic translation initiation factor 3 subunit 8 (110kD) ; Eukaryotic translation initiation factor 3 subunit 8 110kDa; Eukaryotic translation initiation factor 3 subunit 8; Eukaryotic translation initiation factor 3 subunit C
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Epigenetics and Nuclear Signaling
Purification: Antigen affinity purification
Concentration: 0.6 mg/mL
Dilution: IHC 1:40-1:200
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for EIF3C Polyclonal Antibody?

The catalog number for EIF3C Polyclonal Antibody is E-AB-52777.

What sizes are available for EIF3C Polyclonal Antibody?

EIF3C Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does EIF3C Polyclonal Antibody come in?

EIF3C Polyclonal Antibody is available in 4 different pack sizes.

Is EIF3C Polyclonal Antibody in stock?

EIF3C Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EIF3C Polyclonal Antibody?

EIF3C Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for EIF3C Polyclonal Antibody?

Estimated delivery time for EIF3C Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for EIF3C Polyclonal Antibody?

The safety data sheet for EIF3C Polyclonal Antibody is available here: https://789.bio/eb/KCC0mP.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.