MRPS35 Polyclonal Antibody

Specifications

Catalog number

E-AB-52862-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has had confusing nomenclature in the literature. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 3p, 5q, and 10q. MRPS35 (Mitochondrial Ribosomal Protein S35) is a Protein Coding gene. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. GO annotations related to this gene include poly (A) RNA binding and structural constituent of ribosome.

Abbreviation

MRPS35

UniProt

P82673

Host

Rabbit

Reactivity

Human

Immunogen

Fusion protein of human MRPS35

Target

28S ribosomal protein S28;28S ribosomal protein S28; mitochondrial;28S ribosomal protein S35;28S ribosomal protein S35 mitochondrial precursor;28S ribosomal protein S35; mitochondrial; DKFZp762P093; HDCMD11P; MDS023; MGC104278; mitochondrial; Mitochondrial ribosomal protein S28; Mitochondrial ribosomal protein S35; MRP S28; MRP S35; MRP-S28; MRP-S35; MRPS 28; MRPS 35; MRPS28; MRPS35; OTTHUMP00000240420; OTTHUMP00000240422; OTTHUMP00000240424; PSEC0213; RT35; S28mt; S35mt

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling; Metabolism

Purification

Antigen affinity purification

Concentration

0.96 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

37 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG