DUT Polyclonal Antibody

Catalog number E-AB-52896-01

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Price for E-AB-52896-01

Size / count 20 µL

Specifications

Catalog number: E-AB-52896-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.
Abbreviation: DUT
UniProt: P33316
Host: Rabbit
Reactivity: Human; Rat
Immunogen: Fusion protein of human DUT
Target: Deoxyuridine 5' triphosphate nucleotidohydrolase; nuclear isoform; Deoxyuridine 5'-triphosphate nucleotidohydrolase; mitochondrial; Deoxyuridine triphosphatase; dut; DUT; dUTP nucleotidohydrolase; dUTP pyrophosphatase; dUTPase; FLJ20622
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Epigenetics and Nuclear Signaling
Purification: Antigen affinity purification
Concentration: 1.08 mg/mL
Dilution: IHC 1:50-1:300
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for DUT Polyclonal Antibody?

The catalog number for DUT Polyclonal Antibody is E-AB-52896.

What sizes are available for DUT Polyclonal Antibody?

DUT Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does DUT Polyclonal Antibody come in?

DUT Polyclonal Antibody is available in 4 different pack sizes.

Is DUT Polyclonal Antibody in stock?

DUT Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DUT Polyclonal Antibody?

DUT Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for DUT Polyclonal Antibody?

Estimated delivery time for DUT Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for DUT Polyclonal Antibody?

The safety data sheet for DUT Polyclonal Antibody is available here: https://789.bio/eb/9KSeLG.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.