TTC38 Polyclonal Antibody

Specifications

Catalog number

E-AB-52970-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

TTC38 (tetratricopeptide repeat domain 38) is a 469 amino acid protein that contains three TPR repeats and belongs to the TTC38 family. The gene that encodes TTC38 consists of over 26,000 bases and maps to 22q13. Housing over 500 genes, chromosome 22 is the second smallest chromosome in the human genome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. In addition, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Abbreviation

TTC38

UniProt

Q5R3I4

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Fusion protein of human TTC38

Target

LL22NC03-5H6.5; Tetratricopeptide repeat protein 38; TPR repeat protein 38; TTC38; TTC38

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cell Biology

Purification

Antigen affinity purification

Concentration

1.5 mg/mL

Dilution

WB 1:1000-1:5000; IHC 1:50-1:300

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

53 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG