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Product details

NPHP1 Polyclonal Antibody

Catalog number E-AB-53023-01

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Price for E-AB-53023-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-53023-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Abbreviation
NPHP1
UniProt
O15259
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human NPHP1
Target
JBTS4; Juvenile nephronophthisis 1 protein; Nephrocystin 1; nephronophthisis 1 (juvenile) ; Nephronophthisis; NPH1; NPHP1; SLSN1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell Biology; Signal transduction
Purification
Antigen affinity purification
Concentration
1.02 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
83 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

Frequently Asked Questions

What is the catalog number for NPHP1 Polyclonal Antibody?

The catalog number for NPHP1 Polyclonal Antibody is E-AB-53023.

What sizes are available for NPHP1 Polyclonal Antibody?

NPHP1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does NPHP1 Polyclonal Antibody come in?

NPHP1 Polyclonal Antibody is available in 4 different pack sizes.

Is NPHP1 Polyclonal Antibody in stock?

NPHP1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NPHP1 Polyclonal Antibody?

NPHP1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for NPHP1 Polyclonal Antibody?

Estimated delivery time for NPHP1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NPHP1 Polyclonal Antibody?

The safety data sheet for NPHP1 Polyclonal Antibody is available here: https://789.bio/eb/mTC4yH.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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