KRCC1 Polyclonal Antibody

Specifications

Catalog number

E-AB-53125-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

KRCC1 (lysine-rich coiled-coil 1), also known as CHBP2 (cryptogenic hepatitis-binding protein 2), is a 259 amino acid protein that is encoded by a gene located on human chromosome 2p11.2. Consisting of 237 million bases, chromosome 2 is the second largest human chromosome and encodes over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstrm syndrome, is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

Abbreviation

KRCC1

UniProt

Q9NPI7

Host

Rabbit

Reactivity

Human

Immunogen

Fusion protein of human KRCC1

Target

CHBP2; cryptogenic hepatitis binding protein; Cryptogenic hepatitis-binding protein 2; KRCC1; KRCC1; lysine rich coiled coil 1; Lysine-rich coiled-coil protein 1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cell Biology

Purification

Antigen affinity purification

Concentration

1.08 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG