BECN1 Polyclonal Antibody — image 1 of 2

Product details

BECN1 Polyclonal Antibody

Catalog number E-AB-53242-01

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Price for E-AB-53242-01

Size / count 20 µL

Specifications

Catalog number: E-AB-53242-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Abbreviation: BECN1
UniProt: Q14457
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Synthetic peptide of human BECN1
Target: APG6; ATG 6; ATG6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; Beclin 1 (coiled coil moesin like BCL2 interacting protein) ; Beclin 1 autophagy related; Beclin-1; Beclin1; BECN 1; Becn1; BECN1; Coiled coil myosin like BCL2 interacting protein; Coiled-coil myosin-like BCL2-interacting protein; GT197; Protein GT197; VPS 30; VPS30
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Epigenetics and Nuclear Signaling; Metabolism; Microbiology; Signal Transduction
Purification: Antigen affinity purification
Concentration: 0.84 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:50-1:100
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 52 kDa
Observed Molecular Weight: Refer to figures
Citation 01: https://www.sciencedirect.com/science/article/pii/S0020138322006258
Citation 02: https://www.tandfonline.com/doi/abs/10.1080/01616412.2022.2159109
Isotype: IgG

Frequently Asked Questions

What is the catalog number for BECN1 Polyclonal Antibody?

The catalog number for BECN1 Polyclonal Antibody is E-AB-53242.

What sizes are available for BECN1 Polyclonal Antibody?

BECN1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does BECN1 Polyclonal Antibody come in?

BECN1 Polyclonal Antibody is available in 4 different pack sizes.

Is BECN1 Polyclonal Antibody in stock?

BECN1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BECN1 Polyclonal Antibody?

BECN1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for BECN1 Polyclonal Antibody?

Estimated delivery time for BECN1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BECN1 Polyclonal Antibody?

The safety data sheet for BECN1 Polyclonal Antibody is available here: https://789.bio/eb/j5SyD4.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.