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Product details

LEPR Polyclonal Antibody

Catalog number E-AB-53262-01

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Price for E-AB-53262-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-53262-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021) .
Abbreviation
LEPR
UniProt
P48357
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human LEPR
Target
CD 295; CD295; CD295 antigen; Db; Fa; HuB219; LEP R; LEP-R; LEPR; LEPR; LEPRD; Leptin receptor; Leptin receptor fatty; Leptin receptor gene related protein; Leptin receptor precursor; Leptin receptor precursor; OB R gene related protein; OB receptor; OB-R; OB-RGRP; obl; Obr
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction
Purification
Antigen affinity purification
Concentration
0.84 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
133 kDa
Observed Molecular Weight
Refer to figures
Citation 01
https://onlinelibrary.wiley.com/doi/abs/10.1002/mrd.23342
Isotype
IgG

Frequently Asked Questions

What is the catalog number for LEPR Polyclonal Antibody?

The catalog number for LEPR Polyclonal Antibody is E-AB-53262.

What sizes are available for LEPR Polyclonal Antibody?

LEPR Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does LEPR Polyclonal Antibody come in?

LEPR Polyclonal Antibody is available in 4 different pack sizes.

Is LEPR Polyclonal Antibody in stock?

LEPR Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures LEPR Polyclonal Antibody?

LEPR Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for LEPR Polyclonal Antibody?

Estimated delivery time for LEPR Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for LEPR Polyclonal Antibody?

The safety data sheet for LEPR Polyclonal Antibody is available here: https://789.bio/eb/5CSqb5.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

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