Product details

XAB2 Polyclonal Antibody

Catalog number E-AB-53550-01

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Price for E-AB-53550-01

Size / count 20 µL

Specifications

Catalog number: E-AB-53550-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: HCNP, also known as XAB2 (Xeroderma pigmentosum group A (XPA) binding protein 2), HCRN, SYF1 or NTC90, is a nuclear protein that participates in transcription, transcription-coupled repair (TCR) and pre-mRNA splicing. It contains fifteen tetratricopeptide repeat motifs and associates with nucleotide excision repair machinery. More specifically, HCNP associates with Cockayne syndrome group A and B proteins (CSA and CSB), RNA Polymerase II (Pol II) and XPA in response to DNA damage and is believed to function in the TCR pathway. HCNP also functions as an essential component of a pre-mRNA splicing complex of the spliceosome (composed of AQR (aquarius), PRP19, CCDC16, HCNP, ISY1 and Cyclophilin E) and is required for proper RNA synthesis in the cell. In addition, HCNP functions as a component of the RAR corepressor complex with RAR and HDAC3 and exhibits an inhibitory effect on ATRA-induced cell differentiation. This suggests that HCNP may function as useful target in cancer therapy.
Abbreviation: XAB2
UniProt: Q9HCS7
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Synthetic peptide of human XAB2
Target: 0610041O14Rik; adapter protein ATH 55; Adapter protein ATH-55; Ath55; AV025587; Crn related protein kim1 ; crn-related protein kim1; DKFZp762C1015; HCNP; HCNP protein; HCRN; KIAA1177; NTC90; PP3898; Pre-mRNA-splicing factor SYF1; Protein HCNP; RNA splicing factor; SYF1; SYF1 homolog; SYF1 homolog; RNA splicing factor ; SYF1 pre mRNA splicing factor; SYF1; Xab2; XPA binding protein 2; XPA-binding protein 2
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Epigenetics and Nuclear Signaling
Purification: Antigen affinity purification
Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:25-1:100
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 100 kDa
Observed Molecular Weight: Refer to figures
Isotype: IgG

Frequently Asked Questions

What is the catalog number for XAB2 Polyclonal Antibody?

The catalog number for XAB2 Polyclonal Antibody is E-AB-53550.

What sizes are available for XAB2 Polyclonal Antibody?

XAB2 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does XAB2 Polyclonal Antibody come in?

XAB2 Polyclonal Antibody is available in 4 different pack sizes.

Is XAB2 Polyclonal Antibody in stock?

XAB2 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures XAB2 Polyclonal Antibody?

XAB2 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for XAB2 Polyclonal Antibody?

Estimated delivery time for XAB2 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for XAB2 Polyclonal Antibody?

The safety data sheet for XAB2 Polyclonal Antibody is available here: https://789.bio/eb/POWfr5.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.